自从哈佛医学院的研究发现NMN可以逆转衰老,绕让60岁的小鼠身体指标回到20岁的状态,NMN开始被称为“长生不老药“。事实上这种物质是人体固有的,NMN是烟酰胺单核苷酸Nicotinamide mononucleotide的简称, 是NAD+的前体,参与上千种人体的生化反应,是人体重要的辅酶。详情阅读》 |
色氨酸、烟酸、烟酰胺和NMN/NR四种物质可以补充NAD+,色氨酸/烟酸/烟酰胺无法绕过NAMPT酶的限制,NR在胃中会被消化,NMN是补充NAD+最有效的途径: A,通过消化系统完好无损地吸收; B,2~3分钟进入血液; C,15分钟内提升组织中的NMN含量; D,迅速提升血液、肝脏等器官中的NAD+水平; NMN在体内的吸收非常迅速,可以迅速提高体内NAD+水平(如右图):详细阅读》 |
食物类型 | 名称 | Mg/100g食物 |
蔬菜 | 毛豆 | 0.47–1.88 |
蔬菜 | 西兰花 | 0.25–1.12 |
蔬菜 | 黄瓜种子 | 0.56 |
黄瓜皮 | 0.65 | |
蔬菜 | 卷心菜 | 0.0–0.90 |
水果 | 鳄梨 | 0.36–1.60 |
水果 | 番茄 | 0.26–0.30 |
菌类 | 蘑菇 | 0.0–1.01 |
肉 | 牛肉(生) | 0.06–0.42 |
海鲜 | 虾 | 0.22 |
根据FDA的等效原则,一个70Kg的成年人每天应补充600mg的NMN。NMN在食物中富含较多,NMN含量如下表,一个成年人补充同等量的600mg/天的NMN,则需要吃掉32~128kg的毛豆,或者54~240kg的西兰花。而且这还是在保证完全吸收的情况下,这显然是不现实的,补充非食物来源的NMN显得尤为重要。
备注: NMN通过高压液相测定
来源:Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
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